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overview John J. Fung, M.D., Ph.D. is the Director of the UChicago Medicine Transplantation Institute. Prior to that, he served as Chairman of the Cleveland Clinic Health System Center for Transplantation, as well as the former Chief of the Division of Transplant Surgery at the University of Pittsburgh. With over 30 years of involvement in abdominal and cellular transplantation, he is also an accomplished immunologist. Dr. Fung received his B.A. from the Johns Hopkins University in 1975, followed by a Ph.D. in Immunology in 1980 and M.D. in 1982 from the University of Chicago. He completed his surgical residency at the University of Rochester, and a transplant surgery fellowship at the University of Pittsburgh, under the guidance of Dr. Thomas Starzl. Between 1987 and 1988, he served as Director of Histocompatibility Testing at the University of Rochester. In 1989, he joined the faculty at the University of Pittsburgh and held the tenured position as the inaugural Thomas E. Starzl Professor in Surgery. He joined the Cleveland Clinic in 2004 as the Chairman of the Department of General Surgery and Professor of Surgery at the Lerner College of Medicine at Case Western University. He also served as the Medical Director of Allogen Laboratory, one of the largest histocompatibility laboratories in the United States and oversaw transplantation services at five Cleveland Clinic facilities globally. In 2016, he was recruited to serve as the Director of the newly created University of Chicago Medicine Transplantation Institute. Dr. Fung is a member of numerous scientific and surgical societies and served as President of the International Liver Transplantation Society from 1997-1999. He is currently Secretary of the Transplantation Society. He has published over 1,000 articles and book chapters and serves on the editorial board for several medical journals. He is the immediate past Editor-in-Chief for Liver Transplantation, the highest impact factor specialty transplant journal. His principal research interests are in transplantation immunology, immunosuppressive therapies, and liver related immunology. In addition, he has received numerous prestigious lay and professional awards. His research interests are in transplant immunology, liver immunity, immnosuppression, and outcomes analysis. Dr. Fung is active in community affairs and has been a member of the Board of Directors at the Americans for Medical Progress and the Gift of Hope Organ Procurement Organization. He received an honorable discharge from the United States Army Reserve Medical Corps with the rank of Lieutenant Colonel. He and his wife, Beth have four children: Justin, Lauren, Brendan and Shannon.
One or more keywords matched the following items that are connected to Fung, John
Item TypeName
Concept Skin Ulcer
Concept Skin
Concept Transplantation Immunology
Concept Skin Transplantation
Academic Article Chimerism after organ transplantation.
Academic Article The bidirectional paradigm of transplant immunology.
Academic Article Analysis of T lymphocytes infiltrating human hepatic allografts.
Academic Article Mechanisms underlying the development of T-cell tolerance following interruption of signalling at the CD28/B7 and CD40/gp39 interface.
Academic Article Liver graft induced donor specific unresponsiveness without class I and/or class II antigen differences.
Academic Article De novo sirolimus and reduced-dose tacrolimus versus standard-dose tacrolimus after liver transplantation: the 2000-2003 phase II prospective randomized trial.
Academic Article Systemic administration of CTLA4-Ig or anti-CD40 ligand antibody inhibits second-set rejection of mouse liver allografts.
Academic Article Efficacy of FK 506 in the treatment of recalcitrant pyoderma gangrenosum.
Academic Article The two-way paradigm of transplantation immunology.
Academic Article Cell migration and chimerism after whole-organ transplantation: the basis of graft acceptance.
Academic Article Immune cell function testing: an adjunct to therapeutic drug monitoring in transplant patient management.
Academic Article Augmentation of chimerism with perioperative donor bone marrow infusion in organ transplant recipients: a 44 month follow-up.
Academic Article Explanation for loss of the HLA matching effect.
Academic Article Induction of donor-specific transplantation tolerance to skin and cardiac allografts using mixed chimerism in (A + B-->A) in rats.
Academic Article Transplantation unresponsiveness induced by liver allografts in mouse strains with various histocompatibility disparities.
Academic Article Neurologic complications of FK 506.
Academic Article Impact of donor MHC class I or class II antigen deficiency on first- and second-set rejection of mouse heart or liver allografts.
Academic Article The role of liver-derived regulatory dendritic cells in prevention of type 1 diabetes.
Academic Article The effect of thymus transplantation on allograft rejection in thymectomized bone marrow chimeras.
Academic Article Analysis of chronic rejection and obliterative arteriopathy. Possible contributions of donor antigen-presenting cells and lymphatic disruption.
Academic Article Toward tolerance: lessons learned from liver transplantation.
Academic Article High-Resolution HLA Typing for Sensitized Patients: Advances in Medicine and Science Require Us to Challenge Existing Paradigms.
Academic Article Clinical intestinal transplantation: new perspectives and immunologic considerations.
Academic Article Rejection triggers liver transplant tolerance: Involvement of mesenchyme-mediated immune control mechanisms in mice.
Academic Article Immunosuppression for liver transplantation in HCV-infected patients: mechanism-based principles.
Academic Article Successful hamster-to-rat liver xenotransplantation under FK506 immunosuppression induces unresponsiveness to hamster heart and skin.
Academic Article Presensitization by skin grafting from major histocompatibility complex class I or major histocompatibility complex class II deficient mice identifies class I antigens as inducers of allosensitization.
Academic Article Sirolimus for rescue and primary immunosuppression in transplanted children receiving tacrolimus.
Academic Article Split tolerance induced by orthotopic liver transplantation in mice.
Academic Article Sequential infiltration of class I and class II specific alloreactive T cells in human cardiac allografts.
Academic Article Highlights of the Festschrift in honor of Thomas E. Starzl, MD, PHD.
Academic Article Should HLA mismatch acceptability for sensitized transplant candidates be determined at the high-resolution rather than the antigen level?
Academic Article Contrasting effects of myeloid dendritic cells transduced with an adenoviral vector encoding interleukin-10 on organ allograft and tumour rejection.
Academic Article Four-color flow cytometric analysis of peripheral blood donor cell chimerism.
Academic Article Experimental animal model of graft-versus-host disease (GVHD) after small-bowel transplantation: characteristics of the model and application to developing treatment strategies.
Academic Article Adjuvant bone marrow infusion in clinical organ transplant recipients.
Academic Article FK 506 in solid organ transplantation.
Academic Article Low-dose of FK 506 and associated blood levels in allotransplantation of rat liver, heart, and skin.
Academic Article Murine liver allograft transplantation: tolerance and donor cell chimerism.
Academic Article Hamster-to-rat liver xenografts protect extrahepatic organs from rejection.
Academic Article Mouse liver transplantation tolerance: the role of hepatocytes and nonparenchymal cells.
Academic Article The many faces of multivisceral transplantation.
Award or Honor Receipt Irvington Institute for Medical Research Fellow in Immunology
Award or Honor Receipt Thomas Starzl Prize in Surgery and Immunology
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  • skin
  • immunology